Mexican Lasagna : A Bold Tex-Mex Twist

Posted on May 8, 2025 ·

By Lyndy

an enchilada casserole is cut into slices and served on plates

Lasagna is a comfort food classic—but what happens when you give it a spicy Tex-Mex twist? You get this mouthwatering Mexican Lasagna Recipe that’s bold, hearty, and layered with irresistible flavor. It’s everything you love about tacos, enchiladas, and casseroles, stacked together in a warm, cheesy bake.

Whether you’re feeding a crowd or meal prepping for the week, this dish delivers big on taste and ease. With seasoned ground beef, black beans, fire-roasted tomatoes, and gooey cheese between layers of corn tortillas, it’s an all-in-one meal that’s impossible to resist.

📝 Why You’ll Love This Mexican Lasagna Recipe

  • One-Dish Dinner: A full meal baked in one casserole dish.
  • Make-Ahead Friendly: Great for busy weeknights or entertaining.
  • Big Tex-Mex Flavor: Zesty, cheesy, and satisfying.
  • Customizable: Easy to swap in veggies, chicken, or even make it vegetarian.
  • Freezer-Friendly: Perfect for batch cooking and meal prep.

🛒 Ingredients (Serves ~12)

For the Filling:

  • 2 lbs ground beef (or turkey)
  • 1 medium onion, chopped
  • 4 cloves garlic, minced
  • 1 packet taco seasoning (or homemade)
  • 1 (15 oz) can black beans, rinsed and drained
  • 1 (4 oz) can green chiles
  • 1 (15 oz) can fire-roasted tomatoes
  • ½ cup sour cream or Greek yogurt (optional for creaminess)

For Assembly:

  • 18 corn tortillas (or flour if preferred)
  • 6 cups shredded Mexican blend cheese
  • 1 cup salsa or enchilada sauce
  • Chopped cilantro, sliced jalapeños, and avocado for topping (optional)

🕒 Prep & Cook Time

  • Prep Time: 20 minutes
  • Cook Time: 30 minutes
  • Rest Time: 10 minutes
  • Total Time: ~1 hour

👩‍🍳 Instructions

Step 1: Cook the Filling

In a large skillet, cook ground beef and onion over medium-high heat until browned. Add garlic and cook for 1 more minute. Drain excess fat.

Stir in taco seasoning, black beans, green chiles, fire-roasted tomatoes, and sour cream (if using). Simmer for 5–7 minutes to blend flavors.

Step 2: Preheat Oven

Preheat oven to 375°F (190°C). Lightly grease a 9×13-inch casserole dish.

Step 3: Assemble the Lasagna

Spread a thin layer of salsa or enchilada sauce on the bottom. Layer 6 tortillas, overlapping to cover.

Add ⅓ of the beef mixture and 2 cups of cheese. Repeat layers two more times, ending with cheese on top.

Step 4: Bake

Cover with foil and bake for 20 minutes. Uncover and bake an additional 10 minutes until bubbly and golden.

Step 5: Rest & Serve

Let the lasagna sit for 10 minutes before slicing. Top with chopped cilantro, avocado slices, or jalapeños if desired.

🧁 Serving Suggestions

  • Serve with a side of Mexican rice or tortilla chips.
  • Add a fresh salad with lime vinaigrette to balance the richness.
  • Pair with a mango margarita or chilled Mexican lager.

🔄 Variations

  • Vegetarian: Use sautéed zucchini, bell peppers, and mushrooms in place of beef.
  • Spicy: Add chipotle in adobo or extra jalapeños to the filling.
  • Creamy: Mix in a can of cream of chicken or mushroom soup.
  • Low-Carb: Swap tortillas for zucchini slices or use low-carb wraps.

🥶 Storage & Freezing

  • Refrigerator: Store leftovers in an airtight container for up to 4 days.
  • Freezer: Wrap tightly and freeze for up to 3 months.
  • Reheat: Microwave individual portions or bake at 350°F until heated through.

🧬 Estimated Nutrition (Per Serving)

  • Calories: ~420
  • Fat: 25g
  • Carbs: 28g
  • Protein: 23g
  • Fiber: 4g
  • Sodium: 680mg

Based on 12 servings; varies with ingredients and brands.

🌐 External Resources

❓ Frequently Asked Questions – Mexican Lasagna

Can I use flour tortillas instead of corn?
Yes, but corn tortillas hold up better to layering and baking. If using flour, consider toasting them slightly first.

Can I make this dish ahead of time?
Definitely! Assemble it, cover, and refrigerate for up to 24 hours before baking.

Is it possible to make this gluten-free?
Yes—use certified gluten-free corn tortillas and double-check your seasoning packets.

What’s the best way to freeze it?
Wrap tightly in plastic and foil. Label and date. Thaw overnight in the fridge before reheating.

What cheese works best?
A shredded Mexican blend is ideal, but Monterey Jack or sharp cheddar also work great.

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Mexican Lasagna : A Bold Tex-Mex Twist


  • Author: Lyndy
  • Total Time: 1 hour

Description

Lasagna is a comfort food classic—but what happens when you give it a spicy Tex-Mex twist? You get this mouthwatering Mexican Lasagna Recipe that’s bold, hearty, and layered with irresistible flavor.


Ingredients

Scale

For the Filling:

  • 2 lbs ground beef (or turkey)
  • 1 medium onion, chopped
  • 4 cloves garlic, minced
  • 1 packet taco seasoning (or homemade)
  • 1 (15 oz) can black beans, rinsed and drained
  • 1 (4 oz) can green chiles
  • 1 (15 oz) can fire-roasted tomatoes
  • ½ cup sour cream or Greek yogurt (optional for creaminess)

For Assembly:

  • 18 corn tortillas (or flour if preferred)
  • 6 cups shredded Mexican blend cheese
  • 1 cup salsa or enchilada sauce
  • Chopped cilantro, sliced jalapeños, and avocado for topping (optional)


Instructions

Step 1: Cook the Filling

In a large skillet, cook ground beef and onion over medium-high heat until browned. Add garlic and cook for 1 more minute. Drain excess fat.

Stir in taco seasoning, black beans, green chiles, fire-roasted tomatoes, and sour cream (if using). Simmer for 5–7 minutes to blend flavors.

Step 2: Preheat Oven

Preheat oven to 375°F (190°C). Lightly grease a 9×13-inch casserole dish.

Step 3: Assemble the Lasagna

Spread a thin layer of salsa or enchilada sauce on the bottom. Layer 6 tortillas, overlapping to cover.

Add ⅓ of the beef mixture and 2 cups of cheese. Repeat layers two more times, ending with cheese on top.

Step 4: Bake

Cover with foil and bake for 20 minutes. Uncover and bake an additional 10 minutes until bubbly and golden.

Step 5: Rest & Serve

Let the lasagna sit for 10 minutes before slicing. Top with chopped cilantro, avocado slices, or jalapeños if desired.

Notes

  • Serve with a side of Mexican rice or tortilla chips.
  • Add a fresh salad with lime vinaigrette to balance the richness.
  • Pair with a mango margarita or chilled Mexican lager.
  • Prep Time: 20
  • Cook Time: 30
  • Category: Dinner
  • Cuisine: Mexican

Nutrition

  • Serving Size: 12
  • Calories: 420
  • Fat: 25g
  • Carbohydrates: 28g
  • Fiber: 4g
  • Protein: 23g

Keywords: Mexican Lasagna

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