This Baked Cajun Salmon is everything you want in a weeknight dinner: fast, flavorful, and healthy. Perfectly seasoned with smoky Cajun spices and topped with a creamy avocado sauce, this dish checks all the boxes for a satisfying salmon for lunch or dinner. Whether you’re eating clean, following keto, or simply looking to include more fish and veggies in your meals, this recipe is a keeper.
If you’re a fan of flavorful dishes like creamy sun-dried tomato vegan pasta or stuffed acorn squash, you’ll love how this Cajun-spiced salmon blends bold heat with creamy, cooling avocado. It’s quick to make, highly nutritious, and fits right into your list of salmon healthy recipes.
Table of Contents
Why You’ll Love This Cajun-Spiced Salmon Dish
This isn’t your average salmon dinner. It’s a fall salmon recipe that brings the warmth of spice and the coolness of avocado to the table—delivering restaurant-quality flavor in under 30 minutes. Here’s why it deserves a spot in your weekly meal rotation:
- Bakes in under 20 minutes
- Naturally gluten-free and keto-friendly
- Packed with protein and heart-healthy fats
- Easy to prep ahead for salmon lunch ideas
- Great with roasted veggies, rice, or in tacos
Looking for Mexican salmon recipes or something bold and satisfying? This one hits the mark, much like our pumpkin chicken chili, which also layers heat and comfort beautifully.
Ingredients for Baked Cajun Salmon with Avocado Sauce
You only need a few staple ingredients to create this mouthwatering meal.
For the Cajun Salmon:
- 4 salmon fillets (about 6 oz each)
- 2 tbsp olive oil
- 1 tbsp Cajun seasoning (store-bought or homemade)
- 1/2 tsp smoked paprika (optional, for extra depth)
- Salt and pepper to taste
- Juice of 1/2 lemon
For the Avocado Sauce:
- 1 ripe avocado
- Juice of 1 lime
- 1 clove garlic, minced
- 1 tbsp olive oil
- 1–2 tbsp water (to thin the sauce)
- Salt and pepper to taste
- Optional: fresh cilantro or dill
Looking for a twist? Try pairing with this refreshing lavender lemonade for a clean, cool combo.
Step-by-Step Instructions for Perfectly Baked Cajun Salmon
This recipe is incredibly easy to follow, even for beginners.
Step 1: Preheat Your Oven
Set your oven to 400°F (200°C). Line a baking sheet with parchment paper or foil for easy cleanup.
Step 2: Season the Salmon
Pat your salmon fillets dry and place them on the prepared baking sheet. Drizzle with olive oil, then sprinkle generously with Cajun seasoning, paprika, salt, and pepper. Finish with a squeeze of lemon juice.
Step 3: Bake
Bake for 12–15 minutes, depending on thickness, until the salmon flakes easily with a fork and reaches 145°F (63°C) internally.
Step 4: Prepare the Avocado Sauce
While the salmon bakes, blend avocado, lime juice, garlic, olive oil, salt, pepper, and a splash of water until creamy. Add herbs if desired.
Step 5: Serve
Plate the salmon and top with avocado sauce. Pair with your favorite sides—more on that below.
Kitchen Equipment You’ll Need
To make this Baked Cajun Salmon recipe, gather:
- Baking sheet
- Mixing bowls
- Blender or food processor (for the sauce)
- Measuring spoons
- Knife and cutting board
- Spatula or fish turner
No fancy tools—just everyday essentials!
What Goes Well With Salmon: Delicious Pairings & Side Dishes
Wondering what goes well with salmon? Here are delicious ideas to complete your meal:
- Garlicky kale with white beans and lemon
- Roasted carrots, zucchini, or sweet potatoes
- Cilantro lime rice or cauliflower rice for keto
- Pumpkin French toast roll-ups (for brunch pairings)
- Garlic butter corn with melty cheese
This also makes a stunning salad topper or a protein-packed taco filling—like in our chorizo tacos.
Nutritional Benefits of Salmon and Avocado (Perfect for Keto)
This recipe is rich in nutrients and perfect for anyone seeking keto recipes with avocado. Here’s what makes it stand out:
- Salmon is loaded with omega-3 fatty acids, B vitamins, and protein
- Avocado adds healthy fats, fiber, potassium, and creaminess
- Cajun spices boost metabolism and flavor without extra calories
- Low in carbs and high in satiety
Together, they make a meal that fuels your body while delighting your taste buds.
Common Mistakes to Avoid When Baking Salmon
To get that perfect texture and flavor, avoid these pitfalls:
- Overcooking the salmon – It becomes dry quickly, so keep an eye on it
- Skipping seasoning – The Cajun blend brings the magic; don’t skimp
- Using wet fish – Pat it dry to get a better crust and even cooking
- Forgetting to rest – Let it rest 2–3 minutes after baking to hold in juices
These tips are as helpful as those used in our baked chicken legs and other protein-based mains.
Make-Ahead Tips: How to Prep Salmon for Lunch or Dinner
Want to include this in your weekly rotation of salmon for lunch?
- Bake salmon ahead and store in meal-prep containers
- Keep avocado sauce in a separate container to avoid browning
- Reheat gently in the microwave or serve cold over a salad
- Pair with roasted veggies or cheesy root vegetable gratin for a warm meal
It’s as efficient as our make-ahead breakfast bowls, but perfect for lunch or dinner.
Mexican-Inspired Flavors: Why This Works as a Fall Salmon Recipe
The smoky heat of Cajun seasoning, the creamy avocado, and the lime hint all echo the flavors in many Mexican salmon recipes. You can:
- Add salsa, black beans, or corn for a taco bowl
- Wrap in a tortilla for a fish taco
- Serve over a bed of quinoa with pico de gallo
For fall, pair it with seasonal roasted squash or sweet potatoes for an earthy balance—just like in roasted butternut squash.
Easy Substitutions & Recipe Variations
Make this your own with these simple swaps:
- Use trout or cod instead of salmon
- Try Greek yogurt sauce instead of avocado
- Make it dairy-free by skipping any cheese in your sides
- Add jalapeño or chili flakes for extra spice
- Swap Cajun seasoning with taco spice or harissa for variation
Looking for other fresh takes? Try using this as inspiration for vegetarian pasta primavera.
How to Store and Reheat Baked Cajun Salmon
- Refrigerate leftovers for up to 3 days in an airtight container
- Store avocado sauce with plastic wrap touching the surface to prevent browning
- Reheat gently in a pan or microwave to avoid drying out
- Do not freeze the avocado sauce, but salmon can be frozen for up to 2 months
FAQs About Baked Cajun Salmon with Avocado Sauce
Can I grill this instead of baking?
Yes, just grill over medium heat for 4–5 minutes per side.
Is this recipe spicy?
It has a mild heat, but you can adjust the Cajun seasoning to your preference.
What can I use instead of avocado?
Try a tahini or yogurt-based sauce, or even fruit dip for a contrasting sweet element.
Can I make this for meal prep?
Absolutely! It’s a great make-ahead lunch that keeps well in the fridge.
What vegetables go well with it?
Zucchini, carrots, green beans, or cheesy mashed potato puffs make fantastic sides.
Serving & Presentation Tips for Salmon and Veggies
- Serve salmon over a grain bowl for a full meal
- Top with microgreens or radish for color
- Drizzle avocado sauce artistically for visual appeal
- Add roasted veggies on the side for a balanced plate
- Use a wood board or dark plate to contrast the salmon’s golden hue
This presentation works great for guests, just like our apple pie dip with cinnamon sugar chips at holiday gatherings.
Final Thoughts – Share and Subscribe
This Baked Cajun Salmon with Avocado Sauce is a flavor-packed, fuss-free dinner that fits any lifestyle—from keto to clean eating to pescatarian. It’s fast, satisfying, and rich in nutrients, making it one of the best salmon recipes with avocado for any season, especially fall.
If you loved this recipe, share it with your friends and subscribe to the blog for more wholesome, protein-rich dishes made for real-life meal prep.
PrintBold & Zesty Baked Cajun Salmon with Avocado Sauce
- Total Time: 25 minutes
- Yield: 4 servings 1x
Description
This Baked Cajun Salmon is bold, smoky, zesty, and topped with a creamy avocado sauce for the perfect balance of heat and coolness. Ready in under 30 minutes, naturally gluten-free, keto-friendly, and packed with protein, healthy fats, and flavor — it’s an ideal weeknight salmon dinner or meal prep option. With simple ingredients and big taste, this recipe works beautifully for lunch bowls, tacos, salads, or a wholesome fall-inspired entrée.
Ingredients
For the Cajun Salmon:
- 4 salmon fillets (about 6 oz each)
- 2 tbsp olive oil
- 1 tbsp Cajun seasoning
- 1/2 tsp smoked paprika (optional)
- Salt and pepper, to taste
- Juice of 1/2 lemon
For the Avocado Sauce:
- 1 ripe avocado
- Juice of 1 lime
- 1 clove garlic, minced
- 1 tbsp olive oil
- 1–2 tbsp water (to thin)
- Salt and pepper, to taste
- Optional: fresh cilantro or dill
Notes & Variations:
- Swap salmon with cod or trout.
- Use taco seasoning or harissa instead of Cajun spice.
- Make a yogurt-based sauce instead of avocado.
- Add jalapeño or chili flakes for extra heat.
Instructions
- Preheat: Heat oven to 400°F (200°C). Line a baking sheet with parchment or foil.
- Season: Pat salmon dry. Drizzle with olive oil and coat with Cajun seasoning, paprika, salt, pepper, and lemon juice.
- Bake: Bake 12–15 minutes, or until salmon flakes easily and reaches 145°F (63°C).
- Make Sauce: Blend avocado, lime juice, garlic, olive oil, water, salt, and pepper until creamy.
- Serve: Plate salmon and top generously with avocado sauce. Add your favorite sides.
Notes
- Pat salmon dry for best browning.
- Remove salmon from oven as soon as it flakes to avoid dryness.
- Keep avocado sauce airtight with plastic wrap touching the surface to prevent browning.
- Perfect for meal prep — store salmon and sauce separately.
- Use smoked paprika for deeper flavor.
- Prep Time: 10 minutes
- Cook Time: 15 minutes
- Category: Dinner, Seafood, Keto, Clean Eating
- Method: Baking
- Cuisine: Cajun, American
Nutrition
- Serving Size: 1 salmon fillet with sauce
- Calories: 420
- Sugar: 1g
- Sodium: 360mg
- Fat: 28g
- Saturated Fat: 4g
- Unsaturated Fat: 20g
- Trans Fat: 0g
- Carbohydrates: 6g
- Fiber: 3g
- Protein: 34g
- Cholesterol: 95mg
Keywords: Baked Cajun Salmon, Cajun Salmon Recipe, Salmon with Avocado Sauce, Keto Salmon Dinner, Healthy Salmon Recipes, Meal Prep Salmon


